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1

Synthesis of Formacetal-Linked Dinucleotides to Facilitate dsDNA Bending and Binding to the Homeodomain of Pax6

Marian Pitulescu, Marcel Grapp, Ralph Krätzner, Willhart Knepel, Ulf Diederichsen

Journal:

European Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

2

Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB

Elke Oetjen, Daniela Grapentin, Roland Blume, Michael Seeger, Doris Krause, Anke Eggers, Willhart Knepel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2003

Language:

english

File:

PDF, 308 KB

english, 2003

3

The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level

Elke Oetjen, Kai-Martin Thoms, Yvonne Laufer, Daniela Pape, Roland Blume, Pingfeng Li, Willhart Knepel

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 205 KB

english, 2005

4

cAMP- and diacylglycerol-mediated pathways elevate cytosolic free calcium concentration via dihydropyridine-sensitive, ω-conotoxin-insensitive calcium channels in normal rat anterior pituitary cells

Christof Schöfl, Klaus Meier, Doris M. Götz, Willhart Knepel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1989

Language:

english

File:

PDF, 815 KB

english, 1989

5

Intracellular free calcium concentration in rat anterior pituitary cells as indicated by fura-2: effect of arginine-vasopressin

Willhart Knepel, Christof Schöfl

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1987

Language:

english

File:

PDF, 788 KB

english, 1987

6

The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line

Markus Schwaninger, Roland Blume, Elke Oetjen, Willhart Knepel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1993

Language:

english

File:

PDF, 585 KB

english, 1993

7

Arachidonic acid elevates cytosolic free calcium concentration in rat anterior pituitary cells

Willhart Knepel, Christof Schöfl, Doris M. Götz

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1988

Language:

english

File:

PDF, 934 KB

english, 1988

8

A common mechanism of action of the selective serotonin reuptake inhibitors citalopram and fluoxetine: Reversal of chronic psychosocial stress-induced increase in CRE/CREB-directed gene transcription in transgenic reporter gene mice

Ulrike Böer, Christine Noll, Irmgard Cierny, Doris Krause, Christoph Hiemke, Willhart Knepel

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 539 KB

english, 2010

9

Vasopressin release from rat medial basal hypothalamus induced in vitro by angiotensin

Willhart Knepel, Henning Anhut, Doris Nutto, Angelika Holland, Dieter K. Meyer

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 196 KB

english, 1982

10

Vasopressin and β-endorphin release after osmotic and non-osmotic stimuli: effect of naloxone and dexamethasone

Willhart Knepel, Doris Nutto, Henning Anhut, Georg Hertting

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 610 KB

english, 1982

11

Role of vasopressin in the acth response to isoprenaline

Willhart Knepel, Klaus Benner, Georg Hertting

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 696 KB

english, 1982

12

In vitro CRF activity of vasopressin analogs is not related to pressor activity

Willhart Knepel, Lutz Homolka, Mila Vlaskovska

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 262 KB

english, 1983

13

The homeodomain of PAX6 is essential for PAX6-dependent activation of the rat glucagon gene promoter: Evidence for a PH0-like binding that induces an active conformation

Marcel Grapp, Sabine Teichler, Julia Kitz, Payam Dibaj, Corinna Dickel, Willhart Knepel, Ralph Krätzner

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2009

Language:

english

File:

PDF, 777 KB

english, 2009

14

Top concentrations of dynorphin-like immunoreactivity in fractions of rat anterior pituitary cells enriched in gonadotrophs

Willhart Knepel, Markus Schwaninger, Claus Helm, Ludwig Kiesel

Journal:

Year:

1986

Language:

english

File:

PDF, 244 KB

english, 1986

15

Subcellular distribution of dynorphin-like immunoreactivity in rat adenohypophysis in comparison with luteinizing hormone and follicle-stimulating hormone

Michael Schwenk, Rolf Jackisch, Willhart Knepel

Journal:

Year:

1987

Language:

english

File:

PDF, 484 KB

english, 1987

16

Inhibition by morphine and β-endorphin of vasopressin release evoked by electrical stimulation of the rat medial basal hypothalamus in vitro

Willhart Knepel, Wolfgang Reimann

Journal:

Year:

1982

Language:

english

File:

PDF, 297 KB

english, 1982

17

Effect of transection of subfornical organ efferent projections on vasopressin release induced by angiotensin or isoprenaline in the rat

Willhart Knepel, Doris Nutto, Dieter K. Meyer

Journal:

Year:

1982

Language:

english

File:

PDF, 405 KB

english, 1982

18

Effect of neonatal treatment with monosodium glutamate on vasopressin release during foot shock stress in the rat

Willhart Knepel, Doris Nutto, Georg Hertting

Journal:

Year:

1983

Language:

english

File:

PDF, 363 KB

english, 1983

19

Inhibition by β-endorphin of isoprenaline-induced vasopressin release and its reversal by naloxone

Willhart Knepel, Doris Nutto, Georg Hertting

Journal:

Year:

1981

Language:

english

File:

PDF, 458 KB

english, 1981

20

Cholecystokinin releases β-endorphin from the anterior pituitary gland

Dieter K. Meyer, Henning Anhut, Doris Nutto, Margery C. Beinfeld, Willhart Knepel

Journal:

Year:

1982

Language:

english

File:

PDF, 355 KB

english, 1982

21

Release of dynorphin-like immunoreactivity of rat neurohypophysis in comparison to vasopressin after various stimuli in vitro and in vivo

Anhut, Henning, Knepel, Willhart

Journal:

Neuroscience Letters

Year:

1982

Language:

english

File:

PDF, 1.55 MB

english, 1982

22

β-endorphin release by angiotensin II: studies on the mechanism of action

Anhut, Henning, Knepel, Willhart, Holland, Angelika, Meyer, Dieter K.

Journal:

Regulatory Peptides

Year:

1982

Language:

english

File:

PDF, 415 KB

english, 1982

23

β-Endorphin controls vasopressin release during foot shock-induced stress in the rat

Knepel, Willhart, Nutto, Doris, Anhut, Henning

Journal:

Regulatory Peptides

Year:

1983

Language:

english

File:

PDF, 634 KB

english, 1983

24

Progress in Defining the Mechanism of Action of Antidepressants

Dr Markus Schwaninger,Matthias Weisbrod,Willhart Knepel

Journal:

Year:

1997

Language:

english

File:

PDF, 237 KB

english, 1997

25

Potassium Depolarization Elevates Cytosolic Free Calcium Concentration in Rat Anterior Pituitary Cells through 1,4-Dihydropyridine-Sensitive, ω-Conotoxin-Insensitive Calcium Channels*

MEIER, KLAUS, KNEPEL, WILLHART, SCHOFL, CHRISTOF

Journal:

Year:

1988

Language:

english

File:

PDF, 945 KB

english, 1988

26

Glucagon Gene G3 Enhancer: Evidence that Activity Depends on Combination of an Islet-Specific Factor and a Winged Helix Protein

Diedrich, Thomas, Fürstenau, Ursel, Knepel, Willhart

Journal:

Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 1.94 MB

english, 1997

27

Chronic Lithium Salt Treatment Reduces CRE/CREB-Directed Gene Transcription and Reverses Its Upregulation by Chronic Psychosocial Stress in Transgenic Reporter Gene Mice

Böer, Ulrike, Cierny, Irmgard, Krause, Doris, Heinrich, Annette, Lin, Hongyin, Mayr, Georg, Hiemke, Christoph, Knepel, Willhart

Journal:

Neuropsychopharmacology

Year:

2008

Language:

english

File:

PDF, 224 KB

english, 2008

28

Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC

Heinrich, Annette, Böer, Ulrike, Tzvetkov, Mladen, Oetjen, Elke, Knepel, Willhart

Journal:

Bioscience Reports

Year:

2009

Language:

english

File:

PDF, 574 KB

english, 2009

29

Foot Shock Stress-Induced Release of Vasopressin in Adenohypophysectomized and Hypophysectomized Rats*

KNEPEL, WILLHART, PRZEWLOCKI, RYSZARD, NUTTO, DORIS, HERZ, ALBERT

Journal:

Year:

1985

Language:

english

File:

PDF, 1001 KB

english, 1985

30

Tissue-Specific Transcriptional Activity of a Pancreatic Islet Cell-Specific Enhancer Sequence/Pax6-Binding Site Determined in Normal Adult Tissues in Vivo Using Transgenic Mice

Beimesche, Stephan, Neubauer, Andrea, Herzig, Stephan, Grzeskowiak, Rafal, Diedrich, Thomas, Cierny, Irmgard, Scholz, Doris, Alejel, Tahseen, Knepel, Willhart

Journal:

Molecular Endocrinology

Year:

1999

Language:

english

File:

PDF, 1.74 MB

english, 1999

31

In Vitro Adrenocorticotropin/ β -Endorphin-Releasing Activity of Vasopressin Analogs Is Related neither to Pressor nor to Antidiuretic Activity*

KNEPEL, WILLHART, HOMOLKA, LUTZ, VLASKOVSKA, MILA, NUTTO, DORIS

Journal:

Year:

1984

Language:

english

File:

PDF, 773 KB

english, 1984

32

Corelease of Dynorphin-Like Immunoreactivity, Luteinizing Hormone, and Follicle-Stimulating Hormone from Rat Adenohypophysis in Vitro *

KNEPEL, WILLHART, SCHWANINGER, MARKUS, DÖHLER, KLAUS D.

Journal:

Year:

1985

Language:

english

File:

PDF, 875 KB

english, 1985

33

The Pancreatic Islet-Specific Glucagon G3 Transcription Factors Recognize Control Elements in the Rat Somatostatin and Insulin-I Genes

Knepel, Willhart, Vallejo, Mario, Chafitz, James A., Habener, Joel F.

Journal:

Molecular Endocrinology

Year:

1991

Language:

english

File:

PDF, 3.42 MB

english, 1991

34

Enhancement by lithium of cAMP-induced CRE/CREB-directed gene transcription conferred by TORC on the CREB basic leucine zipper domain

Böer, Ulrike, Eglins, Julia, Krause, Doris, Schnell, Susanne, Schöfl, Christof, Knepel, Willhart

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 1.12 MB

english, 2007

35

Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans

Sharma, Sanjeev K., Leinemann, Ulrike, Ratke, Regine, Oetjen, Elke, Blume, Roland, Dickel, Corinna, Knepel, Willhart

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 849 KB

english, 2005

36

Inhibition of Cyclic AMP Response Element-Binding Protein/Cyclic AMP Response Element-Mediated Transcription by the Immunosuppressive Drugs Cyclosporin A and FK506 Depends on the Promoter Context

Siemann, Gero, Blume, Roland, Grapentin, Daniela, Oetjen, Elke, Schwaninger, Markus, Knepel, Willhart

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

37

Cholecystokinin-Like Immunoreactivity of Rat Medial Basal Hypothalamus:Investigations on a Possible Hypophysiotropic Function

Anhut, Henning, Meyer, Dieter K., Knepel, Willhart

Journal:

Neuroendocrinology

Year:

1983

Language:

english

File:

PDF, 1.14 MB

english, 1983

38

Beta-Endorphin and Adrenocorticotropin Release from Rat Adenohypophysis in vitro: Evidence for Local Modulation by Arachidonic Acid Metabolites of the Cyclooxygenase and Lipoxygenase Pathway

Vlaskovska, Mila, Knepel, Willhart

Journal:

Neuroendocrinology

Year:

1984

Language:

english

File:

PDF, 1.67 MB

english, 1984